Deoxyuridine triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001425
Members of this Pool
Members of control pools
POOL001424
Last modified: 10/Sep/2021
Results
Publication
Martínez-Arribas B, Requena CE, Pérez-Moreno G, Ruíz-Pérez LM, Vidal AE, González-Pacanowska D: DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools., Cell Mol Life Sci, 2020

PubMed PMCID
Value 0.1
Dimension pmol/106 cell
Error (standard deviation) 0.06
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication HAP1
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Sherman and Fyfe
Growth conditions IMDM supplemented with 10% FBS and antibiotics; cells were transfected with TK1 silencing siRNA
Treatment
Treatment details/effects silencing of cytosolic thymidine kinase, which catalyzes the formation of dTMP from thymidine
Genes and Proteins
Gene name TK1
Gene identifier 7083
Protein name Thymidine kinase, cytosolic
Protein identifier P04183
Genetic manipulation/variation silencing