DNTP005681
dCTP
dNTP Pool | |
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Pool identifier | POOL001425 |
Members of this Pool |
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Members of control pools |
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POOL001424 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Martínez-Arribas B, Requena CE, Pérez-Moreno G, Ruíz-Pérez LM, Vidal AE, González-Pacanowska D: DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools.,
Cell Mol Life Sci, 2020
PubMed PMCID |
Value | 1.56 | Dimension | pmol/106 cell |
Error (standard deviation) | 0.49 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Cell line/type as in publication | HAP1 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | Sherman and Fyfe |
Growth conditions | IMDM supplemented with 10% FBS and antibiotics; cells were transfected with TK1 silencing siRNA |
Treatment | |
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Treatment details/effects | silencing of cytosolic thymidine kinase, which catalyzes the formation of dTMP from thymidine |
Genes and Proteins | |
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Gene name | TK1 |
Gene identifier | 7083 |
Protein name | Thymidine kinase, cytosolic |
Protein identifier | P04183 |
Genetic manipulation/variation | silencing |