2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001421
Members of this Pool
Members of control pools
POOL001420
Last modified: 10/Sep/2021
Results
Publication
Martínez-Arribas B, Requena CE, Pérez-Moreno G, Ruíz-Pérez LM, Vidal AE, González-Pacanowska D: DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools., Cell Mol Life Sci, 2020

PubMed PMCID
Value 2.53
Dimension pmol/106 cell
Error (standard deviation) 0.65
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication MCF-7
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Sherman and Fyfe
Growth conditions Eagle’s MEM supplemented with 10% FBS and antibiotics; cells were transfected with DCTPP1 silencing siRNA
Treatment
Treatment details/effects silencing of dCTP pyrophosphatase 1, wich hydrolyzes deoxynucleoside triphosphates to the corresponding nucleoside monophosphates
Genes and Proteins
Gene name DCTPP1
Gene identifier 79077
Protein name dCTP pyrophosphatase 1
Protein identifier Q9H773
Genetic manipulation/variation silencing