2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001384
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Hoggard PG, Kewn S, Maherbe A, Wood R, Almond LM, Sales SD, Gould J, Lou Y, De Vries C, Back DJ, Khoo SH, CHARM Study Group.: Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea., AIDS, 2002

PubMed
Value 0.12
Dimension pmol/106 cell
Error (interquartile range) 0.09; 0.23
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Tissue type blood
Cell line/type as in publication peripheral blood mononuclear cells
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Growth conditions HIV patient recieving abacavir, lamivudine and zidovudine for 12 weeks
Treatment
Drug/stress type drug
PubChem 441300 , 60825 , 35370
Applied drug abacavir, lamivudine, zidovudine
Treatment details/effects patients were treated with abacavir, lamivudine and zidovudine, nucleoside analogues
Genes and Proteins
No genes or proteins manipulated.