DNTP005524
dTTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL001382 |
| Members of this Pool |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Hoggard PG, Kewn S, Maherbe A, Wood R, Almond LM, Sales SD, Gould J, Lou Y, De Vries C, Back DJ, Khoo SH, CHARM Study Group.: Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea.,
AIDS, 2002
PubMed |
| Value | 0.56 | Dimension | pmol/106 cell |
| Error (interquartile range) | 0.40; 0.79 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | primary cells |
| Tissue type | blood |
| Cell line/type as in publication | peripheral blood mononuclear cells |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | acid extraction |
| Growth conditions | HIV patient recieving abacavir, lamivudine and zidovudine for 6 weeks |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 441300 , 60825 , 35370 |
| Applied drug | abacavir, lamivudine, zidovudine |
| Treatment details/effects | patients were treated with abacavir, lamivudine and zidovudine, nucleoside analogues |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |