DNTP005520
dTTP
dNTP Pool | |
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Pool identifier | POOL001381 |
Members of this Pool |
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Members of control pools |
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POOL001380 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Hoggard PG, Kewn S, Maherbe A, Wood R, Almond LM, Sales SD, Gould J, Lou Y, De Vries C, Back DJ, Khoo SH, CHARM Study Group.: Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea.,
AIDS, 2002
PubMed |
Value | 0.43 | Dimension | pmol/106 cell |
Error (interquartile range) | 0.27; 0.71 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | primary cells |
Tissue type | blood |
Cell line/type as in publication | peripheral blood mononuclear cells |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | acid extraction |
Growth conditions | HIV patient recieving abacavir, lamivudine, zidovudine and 500 mg hydroxyurea twice a day for 2 weeks |
Treatment | |
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Drug/stress type | drug |
PubChem | 441300 , 60825 , 35370 , 3657 |
Applied drug | abacavir, lamivudine, zidovudine, hydroxyurea |
Treatment details/effects | patients were treated with abacavir, lamivudine and zidovudine, nucleoside analogues, and hydroxyurea, a ribonucleoside diphosphate reductase inhibitor |
Genes and Proteins | |
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No genes or proteins manipulated. | |