Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001379
Members of this Pool
Members of control pools
POOL001378
Last modified: 10/Sep/2021
Results
Publication
Hoggard PG, Kewn S, Maherbe A, Wood R, Almond LM, Sales SD, Gould J, Lou Y, De Vries C, Back DJ, Khoo SH, CHARM Study Group.: Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea., AIDS, 2002

PubMed
Value 0.73
Dimension pmol/106 cell
Error (interquartile range) 0.36; 1.06
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Tissue type blood
Cell line/type as in publication peripheral blood mononuclear cells
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Growth conditions HIV patient recieving abacavir, lamivudine, zidovudine and 500 mg hydroxyurea twice a day
Treatment
Drug/stress type drug
PubChem 441300 , 60825 , 35370 , 3657
Applied drug abacavir, lamivudine, zidovudine, hydroxyurea
Treatment details/effects patients were treated with abacavir, lamivudine and zidovudine, nucleoside analogues, and hydroxyurea, a ribonucleoside diphosphate reductase inhibitor
Genes and Proteins
No genes or proteins manipulated.