DNTP005471
dTTP
| dNTP Pool | |
|---|---|
| This entry does not belong to any pool in the database. |
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Lee MH, Wang L, Chang ZF: The contribution of mitochondrial thymidylate synthesis in preventing the nuclear genome stress.,
Nucleic Acids Res, 2014
PubMed PMCID |
| Value | 0.6 | Dimension | pmol/106 cell |
| Error (unspecified) | 0.13 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| CLO Cell line name | IMR-90 cell (CLO:0006951) |
| Cell line/type as in publication | IMR-90 |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | Ferraro |
| Growth conditions | cells were infected by LacZ shRNA lentivirus (control), then incubated in DMEM supplemented with 0.1% serum for 10 days, then in DMEM supplemented with 0.1% serum and 5 μM thymidine for 8 hours |
| Treatment | |
|---|---|
| Drug/stress type | stress |
| Stress type | starvation |
| Treatment details/effects | serum deprivation |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |