Results
Publication	Hu CM, Chang ZF: Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status., Cancer Res, 2008 PubMed
Value	74.9
Dimension	pmol/106 cell
Error (unspecified)	8.92
Data presentation in publication	diagram

Source
Source organism	human (Homo sapiens) Taxonomy 9606
Sample source	cell line
Cell line/type as in publication	HCT-116 p53 -/- derivative
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	methanol
Remarks to measurement type	Sherman and Fyfe
Growth conditions	cells were cultured McCoy’s 5A medium supplemented with 10% fetal bovine serum, and cells were treated with 1 μmol/L doxorubicin for 24 hours

Treatment
Drug/stress type	drug
PubChem	31703
Applied drug	doxorubicin
Treatment details/effects	cells were treated with doxorubicin, which intercalates between base pairs in the DNA helix, additionally, doxorubicin inhibits topoisomerase II

Genes and Proteins
No genes or proteins manipulated.