Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001358
Members of this Pool
Members of control pools
POOL001357
Last modified: 10/Sep/2021
Results
Publication
Tsao N, Lee MH, Zhang W, Cheng YC, Chang ZF: The contribution of CMP kinase to the efficiency of DNA repair., Cell Cycle, 2015

PubMed PMCID
Value 66.8
Dimension pmol/106 cell
Error (standard deviation) 5.29
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication MCF-7
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Ferraro
Growth conditions Cells were infected with UMP/CMP kinase (CPMK) shRNA lentivirus, then maintained in medium containing 10% fetal bovine serum for 72 hours
Treatment
Treatment details/effects silencing of UMP/CMP kinase (CMPK), which catalyzes CDP formation from CMP
Genes and Proteins
Gene name CMPK1
Gene identifier 51727
Protein name UMP-CMP kinase
Protein identifier P30085
Genetic manipulation/variation silencing