DNTP005107
dTTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL001296 |
| Members of this Pool |
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Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Elstein KH, Mole ML, Setzer RW, Zucker RM, Kavlock RJ, Rogers JM, Lau C: Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.,
Toxicol Appl Pharmacol, 1997
PubMed |
| Value | 77 | Dimension | % |
| Error (95 % confidence interval) | 64; 92 |
| Relative compared to | unspecified control |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
| Sample source | cell line |
| CLO Cell line name | MELC cell (CLO:0007672) |
| Cell line/type as in publication | murine erythroleukemic cell (MELC) |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Growth conditions | samples were collected 24 hours after 10 μM 5-FU treatment for 2 hours and 10 μM thymidine treatment |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 3385 , 5789 |
| Applied drug | 5-Fluorouracil, 2'-Deoxythmyidine |
| Treatment details/effects | Thymidylate synthase inhibition and thyimine nucleoside supplementation (different control) |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |