Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001295
Members of this Pool
Members of control pools
POOL001290
Last modified: 10/Sep/2021
Results
Publication
Elstein KH, Mole ML, Setzer RW, Zucker RM, Kavlock RJ, Rogers JM, Lau C: Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells., Toxicol Appl Pharmacol, 1997

PubMed
Value 117
Dimension %
Error (95 % confidence interval) 98; 140
Relative compared to control
Data presentation in publication numerical
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Sample source cell line
CLO Cell line name MELC cell (CLO:0007672)
Cell line/type as in publication murine erythroleukemic cell (MELC)
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions samples were collected 24 hours after 10 μM 5-FU treatment for 2 hours and 1 mM cytidine treatment
Treatment
Drug/stress type drug
PubChem 3385 , 13711
Applied drug 5-Fluorouracil, 2'-Deoxycytidine
Treatment details/effects Thymidylate synthase inhibition and deoxycytidine nucleoside supplementation
Genes and Proteins
No genes or proteins manipulated.