DNTP005076
dGTP
dNTP Pool | |
---|---|
Pool identifier | POOL001288 |
Members of this Pool |
|
Members of control pools |
---|
POOL001284 |
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Elstein KH, Mole ML, Setzer RW, Zucker RM, Kavlock RJ, Rogers JM, Lau C: Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.,
Toxicol Appl Pharmacol, 1997
PubMed |
Value | 7 | Dimension | pmol/106 cell |
Error (95 % confidence interval) | 5; 9 |
Data presentation in publication | numerical |
Source | |
---|---|
Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
Sample source | cell line |
CLO Cell line name | MELC cell (CLO:0007672) |
Cell line/type as in publication | murine erythroleukemic cell (MELC) |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | 2 hours exposure of asynchronous MELC to 10 μM 5-FU, afterwards 10 μM thymidine treatment for 2 hours |
Treatment | |
---|---|
Drug/stress type | drug |
PubChem | 3385 , 5789 |
Applied drug | 5-Fluorouracil, 2'-Deoxythmyidine |
Treatment details/effects | Thymidylate synthase inhibition and thyimine nucleoside supplementation |
Genes and Proteins | |
---|---|
No genes or proteins manipulated. | |