2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001271
Members of this Pool
Members of control pools
POOL001267
Last modified: 10/Sep/2021
Results
Publication
Elstein KH, Mole ML, Setzer RW, Zucker RM, Kavlock RJ, Rogers JM, Lau C: Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells., Toxicol Appl Pharmacol, 1997

PubMed
Value 43
Dimension %
Error (95 % confidence interval) 30.4; 55.6
Relative compared to control
Data presentation in publication diagram
Source
Source organism brown rat (Rattus norvegicus)
Taxonomy 10116
Animal strain Sprague–Dawley rat
Sample source embryo
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions 4 hours sample after pregnant rat dams were injected subcutaneously with 40 mg/kg 5-FU on gestational day 14
Treatment
Drug/stress type drug
PubChem 3385
Applied drug 5-Fluorouracil
Treatment details/effects Thymidylate synthase inhibition
Genes and Proteins
No genes or proteins manipulated.