Results
Publication	Hofmann H, Logue EC, Bloch N, Daddacha W, Polsky SB, Schultz ML, Kim B, Landau NR: The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus., J Virol, 2012 PubMed PMCID
Value	0.0704
Dimension	pmol/106 cell
Error (unspecified)	0.016
Data presentation in publication	diagram

Source
Source organism	human (Homo sapiens) Taxonomy 9606
Sample source	cell line
CLO Cell line name	U-937 cell (CLO:0009465)
Cell line/type as in publication	U937 cells
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	methanol
Remarks to measurement type	Diamond et al. 2004., single-nucleotide extension assay
Growth conditions	cells were differentiated with phorbol myristic acid (PMA) for 20 h

Treatment
Treatment details/effects	expressing dNTP triphosphohydrolase without a functioning nuclear localization signal

Genes and Proteins
Gene name	SAMHD1
Gene identifier	25939
Protein name	SAMHD1
Protein identifier	Q9Y3Z3
Genetic manipulation/variation	extrachromosomal expression of mutant protein
Mutation in protein	K11A, R12A, and R14A (ΔNLS mutant)