2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Zhang R, Bloch N, Nguyen LA, Kim B, Landau NR: SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells., PLoS One, 2014

PubMed PMCID
Value 0.55
Dimension pmol/106 cell
Error (standard deviation) 0.01
Data presentation in publication diagram
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Animal strain C57BL/6 mice
Sample source primary cells
Tissue type bone marrow-derived macrophages
Cell line/type as in publication bone marrow-derived macrophages (BMDM)
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Diamond et al. 2004., single-nucleotide extension assay
Growth conditions N/A
Treatment
Treatment details/effects silencing of SAMHD1 with siRNA pool
Genes and Proteins
Gene name SAMHD1
Gene identifier 25939
Protein name SAMHD1
Protein identifier Q9Y3Z3
Genetic manipulation/variation silencing