Results
Publication	Koehler SE, Ladner RD: Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition., Mol Pharmacol, 2004 PubMed
Value	0.12
Dimension	pmol/106 cell
Error (standard deviation)	0.1
Data presentation in publication	diagram

Source
Source organism	human (Homo sapiens) Taxonomy 9606
Sample source	cell line
Tissue type	breast tissue
Cell line/type as in publication	MCF-7
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	acid extraction
Remarks to measurement type	Sherman and Fyfe
Growth conditions	24 h with 1 μM FUdR

Treatment
Drug/stress type	drug
PubChem	5790
Applied drug	5-Fluorodeoxyuridine
Treatment details/effects	perturbation of thymidylate synhtesis pathway by silencing dUTPase

Genes and Proteins
Gene name	dut
Gene identifier	1854
Protein name	dUTPase
Protein identifier	P33316
Genetic manipulation/variation	silencing