Results
Publication	Koehler SE, Ladner RD: Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition., Mol Pharmacol, 2004 PubMed
Value	0.1
Dimension	pmol/106 cell
Error	Error not provided.
Data presentation in publication	diagram

Source
Source organism	human (Homo sapiens) Taxonomy 9606
Sample source	cell line
Tissue type	colon
CLO Cell line name	SW620 cell (CLO:0009221)
Cell line/type as in publication	SW620 cancer cell line
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	acid extraction
Remarks to measurement type	Sherman and Fyfe
Growth conditions	24 h with 0 nM FUdR

Treatment
Treatment details/effects	perturbation of thymidylate synhtesis pathway by silencing dUTPase

Genes and Proteins
Gene name	dut
Gene identifier	1854
Protein name	dUTPase
Protein identifier	P33316
Genetic manipulation/variation	silencing