Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001234
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Koehler SE, Ladner RD: Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition., Mol Pharmacol, 2004

PubMed
Value 29
Dimension pmol/106 cell
Error (standard deviation) 1.2
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type colon
CLO Cell line name SW620 cell (CLO:0009221)
Cell line/type as in publication SW620 cancer cell line
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Sherman and Fyfe
Growth conditions 24 h with 0 nM FUdR
Treatment
Drug/stress type stress
Treatment details/effects control silencing with siGFP
Genes and Proteins
No genes or proteins manipulated.