2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001210
Members of this Pool
Members of control pools
POOL001206
Last modified: 10/Sep/2021
Results
Publication
Roy B, Guittet O, Beuneu C, Lemaire G, Lepoivre M: Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide., Free Radic Biol Med, 2004

PubMed
Value 95.6
Dimension %
Error (standard deviation) 5.6
Relative compared to control
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type T4-lymphoblastoid cells
Cell line/type as in publication CEM-SS
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions Human CEM-SS cells were cocultured for 6 h with activated macrophages in the presence of dipyridamole; NO scavenger HbO2 (175 μM)
Treatment
Drug/stress type drug
PubChem 3108 , N/A
Applied drug dipyridamole, HbO2
Treatment details/effects physiological amounts of NO; dipyridamole: salvage pathway inhibitor; HbO2:Guanylate synthase inhibitor
Genes and Proteins
Gene name nos2
Gene identifier 4843
Protein name Nitric oxide synthase, inducible
Protein identifier P35228
Genetic manipulation/variation extrachromosomal protein expression