2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001196
Members of this Pool
Members of control pools
POOL001189
Last modified: 10/Sep/2021
Results
Publication
Roy B, Guittet O, Beuneu C, Lemaire G, Lepoivre M: Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide., Free Radic Biol Med, 2004

PubMed
Value 67.3567
Dimension %
Error Error not provided.
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type T4-lymphoblastoid cells
Cell line/type as in publication CEM-SS
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions Cells incubated for 8 h with macrophages in the presence of dipyridamole; Nitrite exposure: 1.15 μM/h.
Treatment
Drug/stress type drug
PubChem 3108
Applied drug dipyridamole
Treatment details/effects physiological amounts of NO; dipyridamole: salvage pathway inhibitor
Genes and Proteins
Gene name nos2
Gene identifier 4843
Protein name Nitric oxide synthase, inducible
Protein identifier P35228
Genetic manipulation/variation extrachromosomal protein expression