DNTP004754
dCTP
dNTP Pool | |
---|---|
Pool identifier | POOL001186 |
Members of this Pool |
|
Members of control pools |
---|
POOL001180 |
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Roy B, Guittet O, Beuneu C, Lemaire G, Lepoivre M: Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide.,
Free Radic Biol Med, 2004
PubMed |
Value | 36.5079 | Dimension | % |
Error | Error not provided. |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
---|---|
Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
Sample source | cell line |
Tissue type | murine lymphoblastic leukemia |
CLO Cell line name | L-1210 cell (CLO:0007155) |
Cell line/type as in publication | L1210 lymphocytic leukemia cells |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Growth conditions | cocultivated with macrophages previously stimulated by IFN-g/LPS for induction of iNOS expression for 4h in the presence of dipyridamole. Following that cells were removed from the macrophage monolayer and cultivated in fresh medium for 30 min. |
Treatment | |
---|---|
Drug/stress type | drug |
PubChem | 3108 |
Applied drug | dipyridamole |
Treatment details/effects | physiological amounts of NO; dipyridamole: salvage pathway inhibitor |
Genes and Proteins | |
---|---|
Gene name | nos2 |
Gene identifier | 4843 |
Protein name | Nitric oxide synthase, inducible |
Protein identifier | P35228 |
Genetic manipulation/variation | extrachromosomal protein expression |