Results
Publication	Roy B, Guittet O, Beuneu C, Lemaire G, Lepoivre M: Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide., Free Radic Biol Med, 2004 PubMed
Value	19.4444
Dimension	%
Error	Error not provided.
Relative compared to	control
Data presentation in publication	diagram

Source
Source organism	mouse (Mus musculus) Taxonomy 10090
Sample source	cell line
Tissue type	murine lymphoblastic leukemia
CLO Cell line name	L-1210 cell (CLO:0007155)
Cell line/type as in publication	L1210 lymphocytic leukemia cells
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	methanol
Growth conditions	cocultivated with macrophages previously stimulated by IFN-g/LPS for induction of iNOS expression for 4h in the presence of dipyridamole. Following that cells were removed from the macrophage monolayer and cultivated in fresh medium with 10 mM HU for 30 min.

Treatment
Drug/stress type	drug
PubChem	3108;3657
Applied drug	dipyridamole, hydroxyurea
Treatment details/effects	physiological amounts of NO; dipyridamole: salvage pathway inhibitor; HU: RNR inhibitor

Genes and Proteins
Gene name	nos2
Gene identifier	4843
Protein name	Nitric oxide synthase, inducible
Protein identifier	P35228
Genetic manipulation/variation	extrachromosomal protein expression