Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001158
Members of this Pool
Members of control pools
POOL001156
Last modified: 10/Sep/2021
Results
Publication
Chen P, Wu JN, Shu Y, Jiang HG, Zhao XH, Qian H, Chen K, Lan T, Chen CG, Li J: Gemcitabine resistance mediated by ribonucleotide reductase M2 in lung squamous cell carcinoma is reversed by GW8510 through autophagy induction., Clin Sci (Lond), 2018

PubMed
Value 37.6
Dimension %
Error (standard deviation) 4
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type lung
CLO Cell line name SK-MES cell (CLO:0009048)
Cell line/type as in publication SK-MES-1
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects RRM2 silencing
Genes and Proteins
Gene name RRM2
Gene identifier 6241
Protein name Ribonucleoside-diphosphate reductase subunit M2
Protein identifier P31350
Genetic manipulation/variation silencing