2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001157
Members of this Pool
Members of control pools
POOL001156
Last modified: 10/Sep/2021
Results
Publication
Chen P, Wu JN, Shu Y, Jiang HG, Zhao XH, Qian H, Chen K, Lan T, Chen CG, Li J: Gemcitabine resistance mediated by ribonucleotide reductase M2 in lung squamous cell carcinoma is reversed by GW8510 through autophagy induction., Clin Sci (Lond), 2018

PubMed
Value 70.3279
Dimension %
Error (standard deviation) 57.2371
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type lung
CLO Cell line name SK-MES cell (CLO:0009048)
Cell line/type as in publication SK-MES-1
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects RRM1 silencing
Genes and Proteins
Gene name RRM1
Gene identifier 6240
Protein name Ribonucleoside-diphosphate reductase large subunit
Protein identifier P23921
Genetic manipulation/variation silencing