DNTP004596
dTTP
| dNTP Pool | |
|---|---|
| This entry does not belong to any pool in the database. |
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Das SK, Benditt EP, Loeb LA: Rapid changes in deoxynucleoside triphosphate pools in mammalian cells treated with mutagens.,
Biochem Biophys Res Commun, 1983
PubMed |
| Value | 1 | Dimension | fold change |
| Error | Error not provided. |
| Relative compared to | control |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
Chinese hamster
(Cricetulus griseus)
Taxonomy 10029 |
| Sample source | cell line |
| Tissue type | fibroblasts |
| Cell line/type as in publication | V79 |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | Skoog |
| Growth conditions | Exponentially growing V79 cells. Control. No MNNG added. At the end of 1 hr incubation at 37 °C the medium was replaced with fresh medium. 8 h after treatment |
| Treatment | |
|---|---|
| Drug/stress type | drug + stress |
| PubChem | 135436526 |
| Applied drug | 1-Methyl-3-Nitro-1-Nitrosoguanidine |
| Treatment details/effects | mutagen; MNNG treatment caused V79 cells to be blocked in S phase (control) |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |