2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001134
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Hu CM, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EYP, Lee WH: High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells., Cell Metab, 2019

PubMed
Value 1.5558
Dimension fold change
Error (standard deviation) 0.1888
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type mammary epithelial cells
CLO Cell line name MCF 10A cell (CLO:0007599)
Cell line/type as in publication MCF10A
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Ferraro
Growth conditions 3-day culture with 22 mM of glucose.
Treatment
Drug/stress type drug + stress
PubChem 5793
Applied drug Glucose
Treatment details/effects transfection with conrol shRNA
Genes and Proteins
No genes or proteins manipulated.