2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001096
Members of this Pool
Members of control pools
POOL001067
Last modified: 10/Sep/2021
Results
Publication
Hu CM, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EYP, Lee WH: High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells., Cell Metab, 2019

PubMed
Value 0.3447
Dimension fold change
Error (standard deviation) 0.3064
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type pancreatic acinar-to-ductal epithelial-like cells
Cell line/type as in publication non-transformed human pancreatic acinar-to-ductal epithelial-like cells (HPNE) generated from a 52-years old male pancreatic specimen
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Ferraro
Growth conditions cultured with 11 mM concentration of glucose alone for 3 days
Treatment
Drug/stress type drug
PubChem 5793
Applied drug Glucose
Genes and Proteins
No genes or proteins manipulated.