DNTP004358
dTTP
dNTP Pool | |
---|---|
Pool identifier | POOL001093 |
Members of this Pool |
|
Members of control pools |
---|
POOL001080 |
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Hu CM, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EYP, Lee WH: High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.,
Cell Metab, 2019
PubMed |
Value | 0.9191 | Dimension | fold change |
Error (standard deviation) | 0.0383 |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
---|---|
Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | pancreatic ductal epithelial cells |
Cell line/type as in publication | non-transformed human pancreatic ductal epithelial cells (HPDE) generated from a 75-years old male pancreatic specimen |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | Ferraro |
Growth conditions | cultured with the 11 mM glucose with deoxynucleosides (5 μM) for 3 days |
Treatment | |
---|---|
Drug/stress type | drug |
PubChem | 5793 , 13730 , 135398592 , 13711 , 5789 |
Applied drug | Glucose, Deoxyadenosine, Deoxyguanosine, Deoxycytidine, Thymidine |
Genes and Proteins | |
---|---|
No genes or proteins manipulated. | |