DNTP004342
dTTP
dNTP Pool | |
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Pool identifier | POOL001089 |
Members of this Pool |
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Members of control pools |
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POOL001080 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Hu CM, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EYP, Lee WH: High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.,
Cell Metab, 2019
PubMed |
Value | 1.0021 | Dimension | fold change |
Error (standard deviation) | 0.0383 |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | pancreatic ductal epithelial cells |
Cell line/type as in publication | non-transformed human pancreatic ductal epithelial cells (HPDE) generated from a 75-years old male pancreatic specimen |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | Ferraro |
Growth conditions | cultured with the 5.5 mM glucose with nucleosides (50 μM) for 3 days |
Treatment | |
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Drug/stress type | drug |
PubChem | 5793 , 60961 , 135398635 , 6175 , 6029 |
Applied drug | Glucose, Adenosine, Guanosine, Cytidine, Uridine |
Genes and Proteins | |
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No genes or proteins manipulated. | |