Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001044
Members of this Pool
Members of control pools
POOL001043
Last modified: 10/Sep/2021
Results
Publication
Krishnan S, Zhou X, Paredes JA, Kuiper RV, Curbo S, Karlsson A: Transgene expression of Drosophila melanogaster nucleoside kinase reverses mitochondrial thymidine kinase 2 deficiency., J Biol Chem, 2013

PubMed PMCID
Value 36
Dimension pmol/mg tissue
Error (standard error) 4
Data presentation in publication numerical
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Animal strain Dm-dNK+/- TK2-/- mice
Sample source tissue
Tissue type skeletal muscle
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Ferraro
Growth conditions 1-month-old Dm-dNK+/- TK2-/- mice
Treatment
Genes and Proteins
Gene name dnk
Gene identifier 42273
Protein name deoxynucleoside kinase
Protein identifier Q9XZT6
Genetic manipulation/variation extrachromosomal protein expression
Gene name TK2
Gene identifier 57813
Protein name thymidine kinase 2, mitochondrial
Protein identifier Q9R088
Genetic manipulation/variation mutation
Mutation in protein TK2 deficient