2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001042
Members of this Pool
Members of control pools
POOL001034 POOL001035 POOL001035
Last modified: 10/Sep/2021
Results
Publication
Bertoli A, Franco M, Balzarini J, Johansson M, Karlsson A: Altered deoxyribonucleotide pools in T-lymphoblastoid cells expressing the multisubstrate nucleoside kinase of Drosophila melanogaster., FEBS J, 2005

PubMed
Value 11.165
Dimension pmol/106 cell
Error (standard deviation) 0.9709
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name H9 cell (CLO:0003612)
Cell line/type as in publication H9
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type radiactive marking
Growth conditions supplemented with dialyzed serum and 10 μM hydroxyurea (HU)
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Treatment details/effects Ribonucleotide reductase (RNR) inhibitor
Genes and Proteins
Gene name dnk
Gene identifier 42273
Protein name deoxynucleoside kinase
Protein identifier Q9XZT6
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein GFP-fused