Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001030
Members of this Pool
Members of control pools
POOL001026 POOL001028
Last modified: 10/Sep/2021
Results
Publication
Bertoli A, Franco M, Balzarini J, Johansson M, Karlsson A: Altered deoxyribonucleotide pools in T-lymphoblastoid cells expressing the multisubstrate nucleoside kinase of Drosophila melanogaster., FEBS J, 2005

PubMed
Value 72.4435
Dimension pmol/106 cell
Error (standard deviation) 0.9856
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name CCRF-CEM cell (CLO:0002334)
Cell line/type as in publication CCRF-CEM
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type radiactive marking
Growth conditions supplemented with dialyzed serum and 1 μM each of dThd, dAdo, dGuo and dCyd
Treatment
Drug/stress type drug
PubChem 5789 , 636 , 135398592 , 13711
Applied drug deoxythymidine, deoxyadenosine, deoxyguanosine, deoxycytidine
Genes and Proteins
Gene name dnk
Gene identifier 42273
Protein name deoxynucleoside kinase
Protein identifier Q9XZT6
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein GFP-fused