DNTP003971
dATP
| dNTP Pool | |
|---|---|
| This entry does not belong to any pool in the database. |
| Members of control pools |
|---|
| N/A |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Begleiter A, Pugh L, Israels LG, Johnston JB: Enhanced cytotoxicity and inhibition of DNA damage repair in irradiated murine L5178Y lymphoblasts and human chronic lymphocytic leukemia cells treated with 2'-deoxycoformycin and deoxyadenosine in vitro.,
Cancer Res, 1988
PubMed |
| Value | 64.5161 | Dimension | pmol/106 cell |
| Error (standard error) | 20.1613 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
| Sample source | cell line |
| CLO Cell line name | L5178Y cell (CLO:0007195) |
| Cell line/type as in publication | L5178Y |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | acid extraction |
| Remarks to measurement type | Hunting and Henderson |
| Growth conditions | proliferating cells; 5 μM dCF; 50 μM dAdo; incubation for 1h then incubation for 4 another hours; removal of dCF and dAdo 2 hours ago; irradiated with 600 rads 6 hours ago |
| Treatment | |
|---|---|
| Drug/stress type | drug + stress |
| Stress type | UV |
| PubChem | 40926 , 636 |
| Applied drug | 2'-deoxycoformycin, deoxyadenosine |
| Treatment details/effects | irradiated with 600 rads 6 hours ago |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |