2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Begleiter A, Pugh L, Israels LG, Johnston JB: Enhanced cytotoxicity and inhibition of DNA damage repair in irradiated murine L5178Y lymphoblasts and human chronic lymphocytic leukemia cells treated with 2'-deoxycoformycin and deoxyadenosine in vitro., Cancer Res, 1988

PubMed
Value 145.9677
Dimension pmol/106 cell
Error (standard error) 12.0968
Data presentation in publication diagram
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Sample source cell line
CLO Cell line name L5178Y cell (CLO:0007195)
Cell line/type as in publication L5178Y
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Hunting and Henderson
Growth conditions proliferating cells; 5 μM dCF; 50 μM dAdo; incubation for 1h then incubation for 1.5 another hours; irradiated with 600 rads 1.5 hours ago
Treatment
Drug/stress type drug + stress
Stress type UV
PubChem 40926 , 636
Applied drug 2'-deoxycoformycin, deoxyadenosine
Treatment details/effects irradiated with 600 rads 1.5 hours ago
Genes and Proteins
No genes or proteins manipulated.