DNTP003966
dATP
dNTP Pool | |
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This entry does not belong to any pool in the database. |
Members of control pools |
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N/A |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Begleiter A, Pugh L, Israels LG, Johnston JB: Enhanced cytotoxicity and inhibition of DNA damage repair in irradiated murine L5178Y lymphoblasts and human chronic lymphocytic leukemia cells treated with 2'-deoxycoformycin and deoxyadenosine in vitro.,
Cancer Res, 1988
PubMed |
Value | 75.8065 | Dimension | pmol/106 cell |
Error (standard error) | 10.4839 |
Data presentation in publication | diagram |
Source | |
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Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
Sample source | cell line |
CLO Cell line name | L5178Y cell (CLO:0007195) |
Cell line/type as in publication | L5178Y |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | acid extraction |
Remarks to measurement type | Hunting and Henderson |
Growth conditions | proliferating cells; 5 μM dCF; 50 μM dAdo; incubation for 1h then incubation for 30 another minutes; irradiated with 600 rads 30 minutes ago |
Treatment | |
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Drug/stress type | drug + stress |
Stress type | UV |
PubChem | 40926 , 636 |
Applied drug | 2'-deoxycoformycin, deoxyadenosine |
Treatment details/effects | irradiated with 600 rads 30 minutes ago |
Genes and Proteins | |
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No genes or proteins manipulated. | |