DNTP003800
dGTP
dNTP Pool | |
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Pool identifier | POOL000959 |
Members of this Pool |
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Members of control pools | |
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POOL000956 | POOL000957 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Cámara Y, González-Vioque E, Scarpelli M, Torres-Torronteras J, Caballero A, Hirano M, Martí R: Administration of deoxyribonucleosides or inhibition of their catabolism as a pharmacological approach for mitochondrial DNA depletion syndrome.,
Hum Mol Genet, 2014
PubMed PMCID |
Value | 106.5041 | Dimension | pmol/mg protein |
Error (upper interquartile range) | 115.4472 |
Data presentation in publication | diagram |
Source | |
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Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
Animal strain | Tymp−/−/Upp1−/− mice |
Sample source | tissue |
Tissue type | brain |
Compartment | mitochondrion |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | acid extraction |
Remarks to measurement type | Ferraro P et al. Nucleic Acids Res. 2010. |
Growth conditions | 400 mg/kg dCtd |
Treatment | |
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Drug/stress type | drug |
PubChem | 13711 |
Applied drug | deoxycytidine |
Genes and Proteins | |
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Gene name | Tymp |
Gene identifier | 72962 |
Protein name | thymidine phosphorylase |
Protein identifier | Q99N42 |
Genetic manipulation/variation | mutation |
Mutation in protein | knockout |
Gene name | Upp1 |
Gene identifier | 22271 |
Protein name | uridine phosphorylase 1 |
Protein identifier | P52624 |
Genetic manipulation/variation | mutation |
Mutation in protein | knockout |