2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000957
Members of this Pool
Members of control pools
POOL000956
Last modified: 10/Sep/2021
Results
Publication
Cámara Y, González-Vioque E, Scarpelli M, Torres-Torronteras J, Caballero A, Hirano M, Martí R: Administration of deoxyribonucleosides or inhibition of their catabolism as a pharmacological approach for mitochondrial DNA depletion syndrome., Hum Mol Genet, 2014

PubMed PMCID
Value 79.6748
Dimension pmol/mg protein
Error (upper interquartile range) 83.7398
Data presentation in publication diagram
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Animal strain Tymp−/−/Upp1−/− mice
Sample source tissue
Tissue type brain
Compartment mitochondrion
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Ferraro P et al. Nucleic Acids Res. 2010.
Growth conditions N/A
Treatment
Genes and Proteins
Gene name Tymp
Gene identifier 72962
Protein name thymidine phosphorylase
Protein identifier Q99N42
Genetic manipulation/variation mutation
Mutation in protein knockout
Gene name Upp1
Gene identifier 22271
Protein name uridine phosphorylase 1
Protein identifier P52624
Genetic manipulation/variation mutation
Mutation in protein knockout