2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000943
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F: SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates., Nat Immunol, 2012

PubMed PMCID
Value 18.3099
Dimension nM
Error (unspecified) 3.6972
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name U-937 cell (CLO:0009465)
Cell line/type as in publication U937 cells
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type with HIV-1 reverse transcriptase
Growth conditions PMA
Treatment
Drug/stress type drug
PubChem 27924
Applied drug phorbol 12-myristate 13-acetate
Treatment details/effects control transduction
Genes and Proteins
No genes or proteins manipulated.