Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000924
Members of this Pool
Members of control pools
POOL000923
Last modified: 10/Sep/2021
Results
Publication
Dragin L, Nguyen LA, Lahouassa H, Sourisce A, Kim B, Ramirez BC, Margottin-Goguet F: Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply., Retrovirology, 2013

PubMed PMCID
Value 0.4913
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Cell line/type as in publication CD4+ T cells
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type with HIV-1 reverse transcriptase
Growth conditions activated with phytohemaglutinin A; HIV-1 infection; interferon-α (IFN-α), 1000 U/ml, 24h
Treatment
Drug/stress type drug + stress
Stress type viral infection
Applied drug interferon-α (IFN-α)
Treatment details/effects HIV-1 infection
Genes and Proteins
No genes or proteins manipulated.