DNTP003655
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL000922 |
| Members of this Pool |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Dragin L, Nguyen LA, Lahouassa H, Sourisce A, Kim B, Ramirez BC, Margottin-Goguet F: Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply.,
Retrovirology, 2013
PubMed PMCID |
| Value | 6.119 | Dimension | pmol/106 cell |
| Error | Error not provided. |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | primary cells |
| Cell line/type as in publication | monocyte-derived macrophages |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | with HIV-1 reverse transcriptase |
| Growth conditions | HIV-1 infection; 2 mM deoxynucleoside; interferon-α (IFN-α), 100 U/ml, 24h |
| Treatment | |
|---|---|
| Drug/stress type | drug + stress |
| Stress type | viral infection |
| Applied drug | interferon-α (IFN-α) |
| Treatment details/effects | HIV-1 infection |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |