2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000905
Members of this Pool
Members of control pools
POOL000903
Last modified: 10/Sep/2021
Results
Publication
Osei Kuffour E, Schott K, Jaguva Vasudevan AA, Holler J, Schulz WA, Lang PA, Lang KS, Kim B, Häussinger D, König R, Münk C: USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1., J Virol, 2018

PubMed PMCID
Value 0.4115
Dimension pmol/106 cell
Error (standard deviation) 0.0823
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name THP-1 cell (CLO:0009348)
Cell line/type as in publication human myeloid THP-1 cell line
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions PMA (phorbol 12-myristate 13-acetate) -differentiated cells
Treatment
Drug/stress type stress
Treatment details/effects empty USP18 control vector in SAMHD1 KO cells
Genes and Proteins
Gene name SAMHD1
Gene identifier 25939
Protein name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Protein identifier Q9Y3Z3
Genetic manipulation/variation mutation
Mutation in protein knockout