DNTP003520
dUTP
dNTP Pool | |
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This entry does not belong to any pool in the database. |
Members of control pools |
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POOL000882 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Castillo-Acosta VM, Estévez AM, Vidal AE, Ruiz-Perez LM, González-Pacanowska D: Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei.,
Int J Biochem Cell Biol, 2008
PubMed |
Value | 0.82 | Dimension | pmol/106 cell |
Error (unspecified) | 0.03 |
Data presentation in publication | numerical |
Source | |
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Source organism |
Trypanosoma brucei brucei
Taxonomy 5702 |
Sample source | strain |
Cell line/type as in publication | procyclic cell line 449 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | modified Horowitz |
Growth conditions | depletion of dUTPase activity by RNAi; cells grown in the presence of doxycyclin for 8 days |
Treatment | |
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Drug/stress type | drug |
PubChem | 54671203 |
Applied drug | doxycyclin |
Treatment details/effects | depletion of dUTPase activity by RNAi |
Genes and Proteins | |
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Gene name | Tb927.7.5160 |
Gene identifier | 3658718 |
Protein name | Deoxyuridine triphosphatase, putative |
Protein identifier | Q57ZH3 |
Genetic manipulation/variation | silencing |