DNTP003326
dGTP
| dNTP Pool | |
|---|---|
| This entry does not belong to any pool in the database. |
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Balakrishnan K, Nimmanapalli R, Ravandi F, Keating MJ, Gandhi V: Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells.,
Blood, 2006
PubMed PMCID |
| Value | 9.4059 | Dimension | μM |
| Error | Error not provided. |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | primary cells |
| Cell line/type as in publication | chronic lymphocytic leukemia lymphocytes |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | Sherman and Fyfe |
| Growth conditions | after isolation cells were incubated with 2 μM forodesine and 10 μM dGuo at 4 and 8 hours, 8h; patient E |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 135409409 , 135398592 |
| Applied drug | forodesine, deoxyguanosine |
| Treatment details/effects | purine nucleoside phosphorylase (PNP) inhibitor |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |