2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000832
Members of this Pool
Members of control pools
POOL000817
Last modified: 10/Sep/2021
Results
Publication
Davidson MB, Katou Y, Keszthelyi A, Sing TL, Xia T, Ou J, Vaisica JA, Thevakumaran N, Marjavaara L, Myers CL, Chabes A, Shirahige K, Brown GW: Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype., EMBO J, 2012

PubMed PMCID
Value 3.125
Dimension dNTP/NTP * 1000
Error (unspecified) 0.8333
Relative compared to NTP
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain rad54Δ
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions logarithmically growing cells from G1 were released into 0.2 M HU for 60 min
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Treatment details/effects Ribonucleotide reductase (RNR) inhibitor
Genes and Proteins
Gene name RAD54
Gene identifier 852713
Protein name DNA repair and recombination protein RAD54
Protein identifier P32863
Genetic manipulation/variation mutation
Mutation in protein deletion