DNTP003255
dATP
dNTP Pool | |
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Pool identifier | POOL000825 |
Members of this Pool |
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Members of control pools |
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POOL000817 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Davidson MB, Katou Y, Keszthelyi A, Sing TL, Xia T, Ou J, Vaisica JA, Thevakumaran N, Marjavaara L, Myers CL, Chabes A, Shirahige K, Brown GW: Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype.,
EMBO J, 2012
PubMed PMCID |
Value | 0.4878 | Dimension | dNTP/NTP * 1000 |
Error | Error not provided. |
Relative compared to | NTP |
Data presentation in publication | diagram |
Source | |
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Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | pol30^f |
Sample source | strain |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | logarithmically growing cells were arrested in G1 with alpha factor (α) and released into 0.2 M HU; 60 min |
Treatment | |
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Drug/stress type | drug |
PubChem | 3657 |
Applied drug | hydroxyurea |
Treatment details/effects | Ribonucleotide reductase (RNR) inhibitor |
Genes and Proteins | |
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Gene name | POL30 |
Gene identifier | 852385 |
Protein name | Proliferating cell nuclear antigen, PCNA |
Protein identifier | P15873 |
Genetic manipulation/variation | mutation |
Mutation in protein | C-terminally Flag-tagged PCNA, reduced protein levels |