2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000822
Members of this Pool
Members of control pools
POOL000818
Last modified: 10/Sep/2021
Results
Publication
Davidson MB, Katou Y, Keszthelyi A, Sing TL, Xia T, Ou J, Vaisica JA, Thevakumaran N, Marjavaara L, Myers CL, Chabes A, Shirahige K, Brown GW: Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype., EMBO J, 2012

PubMed PMCID
Value 0.4878
Dimension dNTP/NTP * 1000
Error Error not provided.
Relative compared to NTP
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain elg1Δ
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions logarithmically growing cells were arrested in G1 with alpha factor (α) and released into 0.2 M HU; 150 min
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Treatment details/effects Ribonucleotide reductase (RNR) inhibitor
Genes and Proteins
Gene name ELG1
Gene identifier 854315
Protein name Telomere length regulation protein ELG1
Protein identifier Q12050
Genetic manipulation/variation mutation
Mutation in protein deletion