2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000799
Members of this Pool
Members of control pools
POOL000796
Last modified: 10/Sep/2021
Results
Publication
Taylor HE, Simmons GE Jr, Mathews TP, Khatua AK, Popik W, Lindsley CW, D'Aquila RT, Brown HA: Phospholipase D1 Couples CD4+ T Cell Activation to c-Myc-Dependent Deoxyribonucleotide Pool Expansion and HIV-1 Replication., PLoS Pathog, 2015

PubMed PMCID
Value 0.1212
Dimension pmol/106 cell
Error (standard deviation) 0.0162
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Tissue type blood
Cell line/type as in publication primary human resting CD4+ T cells
Compartment whole cell
Experiment Details
Measurement type LC-MS
Extraction method methanol
Growth conditions stimulated with PHA/IL2; 1mM HU for 48h
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Treatment details/effects Ribonucleotide reductase (RNR) inhibitor
Genes and Proteins
No genes or proteins manipulated.