DNTP002967
dGTP
dNTP Pool | |
---|---|
Pool identifier | POOL000761 |
Members of this Pool |
|
Members of control pools |
---|
POOL000760 |
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Cerritelli SM, Iranzo J, Sharma S, Chabes A, Crouch RJ, Tollervey D, El Hage A: High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.,
Nucleic Acids Res, 2020
PubMed PMCID |
Value | 3.09 | Dimension | pmol/108 cell |
Error (standard error of the mean) | 3.05 |
Data presentation in publication | diagram |
Source | |
---|---|
Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | BY4741 |
Sample source | strain |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | HPLC-UV |
Extraction method | acid extraction |
Remarks to measurement type | Watt et al. 2016 |
Growth conditions | N/A |
Treatment |
---|
Genes and Proteins | |
---|---|
Gene name | RNR1 |
Gene identifier | 856801 |
Protein name | ribonucleotide reductase |
Protein identifier | P21524 |
Genetic manipulation/variation | mutation |
Mutation in protein | RNR1 gene is tagged (3HA-RNR1) and is under the control of the PGAL1/10 promoter |