DNTP002966
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL000761 |
| Members of this Pool |
|
| Members of control pools |
|---|
| POOL000760 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Cerritelli SM, Iranzo J, Sharma S, Chabes A, Crouch RJ, Tollervey D, El Hage A: High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.,
Nucleic Acids Res, 2020
PubMed PMCID |
| Value | 34.21 | Dimension | pmol/108 cell |
| Error (standard error of the mean) | 4.39 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
| Bacterial or fungal strain | BY4741 |
| Sample source | strain |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Remarks to measurement type | Watt et al. 2016 |
| Growth conditions | N/A |
| Treatment |
|---|
| Genes and Proteins | |
|---|---|
| Gene name | RNR1 |
| Gene identifier | 856801 |
| Protein name | ribonucleotide reductase |
| Protein identifier | P21524 |
| Genetic manipulation/variation | mutation |
| Mutation in protein | RNR1 gene is tagged (3HA-RNR1) and is under the control of the PGAL1/10 promoter |